姓 名：王文君
职 称：教授，博导
学科方向：食品科学
电 话：0791-83813655
邮 箱：wwjun9999@jxau.edu.cn
社会兼职：
教育部食品科学与工程类教学指导委员会委员
江西省普通高等学校食品科学与工程类教学指导委员会副主任委员
江西省人民政府学位委员会第二届学科评议组工学（Ⅱ）成员
江西省营养学会副理事长
江西省食品科学技术学会常务理事
中国营养学会会员
《食品科学》杂志、《江西农业大学学报》、《食品安全质量检测学报》编委
教育经历
1991-1995江西农业大学畜牧兽医系畜牧专业 本科
1998-2001 江西农业大学动物遗传育种与繁殖专业 硕士
2003-2006 中国农业大学生物学院生物化学与分子生物学 博士
工作经历
1995-1998 江西省供销社江西远大实业发展有限公司
2001-2005 必威讲师
2005-2011 必威副教授
20011-至今 必威教授
研究领域及方向
分子营养学
食品化学
教授课程
本科生课程：食品化学，食品生物化学
研究生课程：现代食品化学，分子营养学
科研项目
先后主持20多项国家、省部级科研项目， 与企业保持紧密合作，承担多项企业合作项目，累计经费300多万元。主持的课题包括：
1. 江西省主要学科学术和技术带头人计划资助项目“青钱柳多糖分子修饰及对树突状细胞免疫调节作用和分子机制研究” 2018-2020
2. 国家自然科学基金项目“基于AMPK信号通路的青钱柳多糖调控脂代谢相关基因DNA甲基化的研究” 2016-2019
3. 国家自然科学基金项目“青钱柳多糖对糖脂代谢的影响及分子机制的研究”，2012-2015
4. 江西现代农业科研协同创新专项“肉鸡产品营养品质评价及调控技术研究”，2017-2019
5. 江西省科技厅重点项目“松针及其提取物调控肉鸡免疫功能关键技术研究及示范” 2016-2018
6. 江西省科技厅重点项目“苜蓿黄酮调控鸡肌肉品质分子机制及绿色饲料添加剂的研制” 2014-2016
7. 江西省高等学校科技落地计划项目“青钱柳多糖对糖脂代谢相关基因DNA甲基化和表达的影响” 2014-2016
8. 江西省自然科学基金项目 “青钱柳多糖对高脂血症大鼠Leptin、PPARγ、MC4R基因DNA甲基化的影响” 2014-2016
9. 江西省科技厅重点项目“青钱柳多糖降血脂分子机制的研究和复方速溶茶的研制” 2009-2011
发表论文情况：（*表示通讯作者）
作为第一作者、通讯作者发表论文80多篇，其中SCI期刊论文40多篇。
1. Xiang Li, Si Chen, Ke-Hui Ouyang, Wen-Jun Wang*. Effects of polysaccharides from Yingshan Yunwu tea on free amino acids, flavor nucleotides and antioxidant abilities in chickens.Research in Veterinary Science, 2022, 149: 11–20 https://doi.org/10.1016/j.rvsc.2022.06.003
2. Yi Han, Yang Zhang, Kehui Ouyang, Lingli Chen, MengZhao, Wenjun Wang*. Sulfated Cyclocarya paliurus polysaccharides improve immune function of immunosuppressed mice by modulating intestinal microbiota. International Journal of Biological Macromolecules, 2022, 212: 31-42 https://doi.org/10.1016/j.ijbiomac.2022.05.110
3. Lin Luo#, Jie Ni#, Mengyun Zhou#, Chunyi Wang, Wen Wen, Jingjie Jiang, Yongran Cheng, Xingwei Zhang, Mingwei Wang*, Wenjun Wang*. Food safety knowledge, attitudes, and self-reported practices among medical staff in China before, during and after the COVID-19 pandemic. Risk Management and Healthcare Policy, 2021, 14: 5027–5038 (ISSN: 1179-1594) https://doi.org/10.2147/RMHP.S339274
4. Ling-Li Chen, Wen-Jun Wang*. p53 regulates lipid metabolism in cancer. International Journal of Biological Macromolecules, 2021, 192: 45–54 https://doi.org/10.1016/j.ijbiomac.2021.09.188
5. Yang Zhang, Yi Han, Jing He, Kehui Ouyang, Meng Zhao, Lei Cai, Zitong Zhao,Wenya Meng, Lingli Chen, Wenjun Wang*. Digestive properties and effects of Chimonanthus nitens Oliv polysaccharides on antioxidant effects in vitro and in immunocompromised mice. International Journal of Biological Macromolecules, 2021, 85: 306–316 https://doi.org/10.1016/j.ijbiomac.2021.06.114
6. ZhanweiYang, JingZhao, Jing'enLi, JinWang, WenjunWang∗. Genome-wide DNA methylation profiling of high-fat emulsion-induced hyperlipidemia mice intervened by a polysaccharide from Cyclocarya paliurus (Batal) Iljinskaja. Food and Chemical Toxicology, 2021, 112230 https://doi.org/10.1016/j.fct.2021.112230
7. Yi Han, Meng Zhao, Kehui Ouyang, Si Chen, Yang Zhang, Xin Liu, Qi An, Zitong Zhao,Wenjun Wang*. Sulfated modification, structures, antioxidant activities and mechanism ofCyclocarya paliurus polysaccharides protecting dendritic cells againstoxidant stress. Industrial Crops & Products 164 (2021) 113353 https://doi.org/10.1016/j.indcrop.2021.113353
8. Meng-Zhao, Yi-Han, Jing'en Li, Qi-An, Ximei Ye, Xiang-Li, Zitong Zhao, Yang-Zhang, Jing-He, Qihuan,Deng, Wenjun Wang*. Structural characterization and antioxidant activity of an acetylated Cyclocarya paliurus polysaccharide (Ac-CPP0.1). International Journal of Biological Macromolecules.2021, 171:112-122 https://doi.org/10.1016/j.ijbiomac.2020.12.201
9. Qi An, Ximei Ye, Yi Han, Meng Zhao, Si Chen, Xin Liu, Xiang Li, Zitong Zhao, Yang Zhang,Kehui Ouyang, Wenjun Wang*. Structure analysis of polysaccharides purified from Cyclocarya paliurus with DEAE-Cellulose and its antioxidant activity in RAW264.7 cells, International Journal of Biological Macromolecules.2020, 157: 604-615 https://doi.org/10.1016/j.ijbiomac.2019.11.212
10. Yi Han, Kehui Ouyang, Jingen Li, Xin Liu, Qi An, Meng Zhao, Si Chen, Xiang Li, Ximei Ye, Zitong Zhao, Lei Cai, Wenjun Wang*. Sulfated modification, characterization, immunomodulatory activities and mechanism of the polysaccharides from Cyclocarya paliurus on dendritic cells. International Journal of Biological Macromolecules. 2020, 159: 108–116 https://doi.org/10.1016/j.ijbiomac.2020.04.265
11. Ximei Ye, Qi An, Si Chen, Xin Liu, Ning Wang, Xiang Li, Meng Zhao, Yi Han, Zitong Zhao, Kehui Ouyang, Wenjun Wang*. The structural characteristics, antioxidant and hepatoprotection activities of polysaccharides from Chimonanthus nitens Oliv. Leaves, International Journal of Biological Macromolecules. 2020, 156: 1520-1529 https://doi:10.1016/j.ijbiomac.2019.11.200
12. Xin Liu, Yangping Wen, Wenjun Wang*, Zitong Zhao, Yi Han, Kaijie Tang, Dan Wang*. Nanobody-based electrochemical competitive immunosensor for the detection of AFB1 through AFB1-HCR as signal amplifier. Microchimica Acta 187(6): 352: 352 (2020). https://doi.org/10.1007/s00604-020-04343-2
13. Lei-Xiong#, Ke-Hui Ouyang#, Hui-Chen, Zhan-Wei Yang, Wen-Bing Hu, Ning-Wang, Xin-Liu, Wen-Jun Wang*. Immunomodulatory effect of Cyclocarya paliurus polysaccharide in cyclophosphamide induced immunocompromised mice. Bioactive Carbohydrates and Dietary Fibre, 2020, 24, 100224, https://doi.org/10.1016/j.bcdf.2020.100224
14. Jingen Li, Qihuan Deng, Xiaoyun Yu, Wenjun Wang*. Structural studies of a new fraction obtained by gradient ethanol precipitation from Acacia seyal gum. Food Hydrocolloids,2020,107:105932 https://doi.org/10.1016/j.foodhyd.2020.105932
15. Xiang-Li, Si-Chen, Zi-Tong Zhao, Meng-Zhao, Yi-Han, Xi-Mei Ye, Qi-An, Ke-Hui Ouyang*, Wen-Jun Wang*. Effects of polysaccharides from Yingshan Yunwu tea on meat quality, immune status and intestinal microflora in chickens. International Journal of Biological Macromolecules. 2020, 155: 61-70 https://doi.org/10.1016/j.ijbiomac.2020.03.198
16. Qi An, Ximei Ye, Yi Han, Meng Zhao, Si Chen, Xin Liu, Xiang Li, Zitong Zhao, Yang Zhang, Kehui Ouyang, Wenjun Wang*. Structure analysis of polysaccharides purified from Cyclocarya paliurus with DEAE-Cellulose and its antioxidant activity in RAW264.7 cells, International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2019.11.212
17. Ning Wang, Xin Liu, Jingen Li, Qingfeng Zhang, Xiang Li, Qi An, Ximei Ye, Zitong Zhao, Lei Cai, Yi Han, Meng Zhao, Wang Wenjun*. Antibacterial mechanism of the synergistic combination between streptomycin and alcohol extracts from the Chimonanthus salicifolius S. Y. Hu. Leaves. Journal of Ethnopharmacology, 2020, 250: 112467 https://doi.org/10.1016/j.jep.2019.112467
18. Ximei Ye, Qi An, Si Chen, Xin Liu, Ning Wang, Xiang Li, Meng Zhao, Yi Han, Zitong Zhao, Kehui Ouyang, Wenjun Wang*. The structural characteristics, antioxidant and hepatoprotection activities of polysaccharides from Chimonanthus nitens Oliv. Leaves, International Journal of Biological Macromolecules. https://doi:10.1016/j.ijbiomac.2019.11.200
19. Si Chen, Xiang Li, Xin Liu, Ning Wang, Qi An, Xi Mei Ye, Zi Tong Zhao, Meng Zhao, Yi Han, Ke Hui Ouyang, and Wenjun Wang*. Investigation of Chemical Composition, Antioxidant Activity, and the Effects of Alfalfa Flavonoids on Growth Performance. Oxidative Medicine and Cellular Longevity, 2000, Volume 2020, Article ID 8569237, 11 pages, https://doi.org/10.1155/2020/8569237
20. S. Chen, K.-H. Ouyang, R.-M. Wu, P. Guo, W.-J. Wang* and D. Wang*. A sensitive semi-quantitative analysis of patent blue v in drinks with SERS. Quality Assurance and Safety of Crops & Foods. 2019, 11 (8): 781-788
21. Xiang-Li, Si-Chen, Jing-En Li, Ning-Wang, Xin-Liu, Qi-An, Xi-Mei Ye, Zi-Tong Zhao, Meng-Zhao, Yi-Han, Ke-Hui Ouyang*, Wen-Jun Wang*. Chemical composition and antioxidant activities of polysaccharides from YingshanCloud Mist Tea. Oxidative Medicine and Cellular Longevity, 2019, Volume 2019, Article ID 1915967 https://doi.org/10.1155/2019/1915967
22. Mei Shu, Yang Xu, Jie-xian Dong, Chan Zhong, Bruce D. Hammock, Wen-jun Wang*, Guo-ping Wu*. Development of a noncompetitive idiometric nanobodies phage immumoassay for the determination of fumonisin B1. Food and Agricultural Immunology, 2019, 30(1), 510–521https://doi.org/10.1080/09540105.2019.1604637
23. Lei-Xiong#, Wen-Bing Hu#, Zhan-Wei Yang, Hui-Chen, Wang-Ning, Liu-Xin, Wen-Jun Wang*. Enzymolysis-ultrasonic assisted extraction of flavanoid from Cyclocarya paliurus (Batal) Iljinskaja: HPLC profile, antimicrobial and antioxidant activity. Industrial Crops & Products, 2019, 130: 615–626 https://doi.org/10.1016/j.indcrop.2019.01.027
24. Zhanwei Yang, Jing Zhao, Jin Wang, Jingen Li, Kehui Ouyang*, Wenjun Wang*. Effects of Cyclocarya paliurus polysaccharide on lipid metabolism-related genes DNA methylation in rats. International Journal of Biological Macromolecules. 2019, 123(2): 343-349 https://doi.org/10.1016/j.ijbiomac.2018.11.110
25. 熊磊，陈慧，王宁，刘鑫，李祥格，吴国强，李景恩，王文君*。黄金茶多糖结构初探及除蛋白工艺研究。江西农业大学学报，2018，40（4）：817-824 https://doi.org/10.13836/j.jjau.2017104
26. Hui Chen, Lei Xiong, Ning Wang, Xin Liu, Wenbing Hu, Zhanwei Yang, Yan Jiang, Guodong Zheng, Kehui Ouyang* and Wen-Jun Wang*. Chimonanthus nitens Oliv. leaf extract exerting anti-hyperglycemic activity by modulating GLUT4 and GLUT1 in the skeletal muscle of a diabetic mouse model. Food & Function, 2018, 9, 4959-4967 https://doi.org/10.1039/c8fo00954f
27. Ning Wang, Hui Chen, Lei Xiong, Xin Liu, Xiang Li, Qi An, Ximei Ye, Wen-Jun Wang*. Phytochemical profile of ethanolic extracts of Chimonanthus salicifolius S. Y. Hu. leaves and its antimicrobial and antibiotic-mediating activity. Industrial Crops and Products 2018,125: 328–334 https://doi.org/10.1016/j.indcrop.2018.09.021
28. Wen-Bing Hu#, Ke-Hui Ouyang#, Guo-Qiang Wu, Hui Chen, Lei Xiong, Xin Liu, Ning Wang, Wen-Jun Wang*. Hepatoprotective effect of flavonoid-enriched fraction from Cyclocarya paliurus leaves on LPS/D-GalN-induced acute liver failure. Journal of Functional Foods,2018, 48:337–350 (https://doi.org/10.1016/j.jff.2018.07.031)
29. Xin Liu#, Dan Wang#, Jinshen Chu, Yang Xu, Wenjun Wang*. Sandwich pair nanobodies, a potential tool for electrochemical immunosensing serum prostate-specific antigen with preferable specificity. Journal of Pharmaceutical and Biomedical Analysis, 2018,158: 361–369, https://doi.org/10.1016/j.jpba.2018.06.021
30. 王宁，林小翠，王文君*。响应面法优化黄金茶总黄酮提取工艺及对胰蛋白酶活性影响的研究。现代食品科技，2018，34（3）：1-10 https://doi.org/10.13982/j.mfst.1673-9078.2018.03.018
31. Zhanwei Yang, Jin Wang, Jingen Li, Lei Xiong, Hui Chen, Xin Liu, Ning Wang , Kehui Ouyang*, Wenjun Wang*. Antihyperlipidemic and hepatoprotective activities of polysaccharide fraction from Cyclocarya paliurus in high-fat emulsion-induced hyperlipidaemic mice. Carbohydrate Polymers, 2018, 183: 11–20 https://doi.org/10.1016/j.carbpol.2017.11.033
32. Lei Xiong#, Ke-Hui Ouyang#, Yan Jiang, Zhan-Wei Yang, Wen-Bing Hu, Hui Chen, Ning Wang, Xin Liu, Wen-Jun Wang*. Chemical composition of Cyclocarya paliurus polysaccharide and inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophage. International Journal of Biological Macromolecules. 2018,107: 1898-1907 https://doi.org/10.1016/j.ijbiomac.2017.10.055
33. 熊磊，陈慧，胡文兵，杨占威，王文君*。黄金茶多糖超声提取工艺及体外抗氧化研究。江西农业大学学报（自然科学版），2017，39( 4) : 801－809 https://doi.org/10.13836 /j.jjau.2017104
34. Hui Chen, Yan Jiang, Zhanwei Yang, Wenbing Hu, Lei Xiong, Ning Wang, Xin Liu, Guodong Zhen, Kehui Ouyang*, Wenjun Wang*. Effect of Chimonanthus nitens Oliv. leaves extract on glycolipid metabolism and antioxidant capacity in diabetic model mice. Oxidative Medicine and Cellular Longevity, 2017, Volume 2017 (2017), Article ID 7648505, 11 pages，https://doi.org/10.1155/2017/7648505
35. 陈慧，熊磊，王文君*。植物次生代谢产物来源的α-葡萄糖苷酶抑制剂研究进展。中国中药杂志，2017，42（15）：2915-2924
36. Wen-Bing Hu, Jing Zhao, Hui Chen, Lei Xiong, Wen-Jun Wang*. Polysaccharides from Cyclocarya paliurus: Chemical composition and lipid-lowering effect on rats challenged with high-fat diet. Journal of Functional Foods, 2017, 36: 262-273 http://dx.doi.org/10.1016/j.jff.2017.07.020
37. 陈 思，郭平，万建春，骆鹏杰，吴瑞梅，王文君*。白酒中糖精钠添加剂表面增强拉曼光谱快速检测研究。光谱学与光谱分析，2017，37 (05)：1412-1417 https://doi.org/10.3964/j.issn.1000-0593
38. 胡文兵，杨占威，陈慧，熊磊，彭俊，王文君*。Plackett-Burman和Box-Behnken试验设计优化超声波－酶法提取青钱柳多糖工艺及结构初探。天然产物研究与开发，2017，29（4）：671-679 https://doi.org/10.16333/j.1001-6880.2017.4.024
39. 赵静，吴茹，李楠，杨占威，胡文兵，王文君*。青钱柳多糖对高脂血症小鼠SOD、 GSH-PX、CAT基因mRNA表达的影响。江苏农业科学，2017，45（4）：124-127 https://doi.org/10.15889/j.issn.1002-1302.2014.04.039
40. Guoqiang Wu, Zhengguo Lin, Liang Li, Lei Zhang, Yanping Hong, Wenjun Wang*, Chao Chen, Yan Jiang, Xianzai Yan. Experiments and kinetics of the epoxidation of allyl chloride with H2O2 over organic base treated TS-1 catalysts. Chemical Engineering Journal, 2017,320: 1-10 http://dx.doi.org/10.1016/ j.cej.2017. 03.030
41. Hui Chen, Ke-Hui Ouyang, Yan Jiang, Zhan-Wei Yang, Lei Xiong, Ning Wang, Xing Liu, Wen-Jun Wang*. Constituent Analysis of the Ethanol Extracts of Chimonanthus nitens Oliv. Leaves and Their Inhibitory Effect on α-Glucosidase Activity. International Journal of Biological Macromolecules, 2017,98: 829-836 https://doi.org/10.1016/j.ijbiomac.2017.02.044
专利获得情况：
Use ethanolic extracts of Chimonanthus Salicifilius S. Y. Hu. in preparation of untibiotic-modulating agents，专利授权号：2020102144，澳大利亚，2020，
一种绵羊瘤胃上皮细胞的分离培养方法，专利授权号：ZL 2017 1 0363364.X，2020
一种节能型智能化滚筒式茶叶杀青及炒干装置，专利授权号：ZL 2018 2 1602376.X，2018
一种优质肉鸡用饲料添加剂的制备及其应用，专利授权号：ZL20150366994.3，2018
咖啡酰奎宁酸制备方法与应用，ZL201310133693.7，2015
一种祛痰止咳组合物及其制备方法，专利授权号：ZL 201210271132.9，2015
一种放牧牛用饲草补料器 ZL 2015 2 1012895.7，2016
获得奖励
青钱柳综合开发与利用研究江西省科技进步二等奖(第5) 2007
青钱柳综合开发与利用研究江西省高等学校科技成果奖二等奖(第4) 2007
猪生长发育性状候选基因遗传变异的研究江西省高等学校科技成果奖三等奖(第1) 2007
中国食品产业科研创新发展“杰出科研人才奖”，中国食品杂志社，2015
畜牧业对鄱阳湖草地群落及生态系统的影响，中国草业科技奖三等奖，第二，2015
指导的研究生分别于2013、2016-2020年获得省级优秀硕士学位论文